Yu-Ju Lee, Ph.D.

• Ph.D. in Translational Biology and Molecular Medicine, Baylor College of Medicine, USA
• M.S. Georgetown University, USA​​
• Yu-Ju is interested in using advanced molecular and neurobiology methods to study therapies for SMS. She is also interested in neuronal miswiring underlying neurogenesis and neurodevelopmental disorders. In her spare time, she likes to watch movies and cartoons, listen to music, and play puzzles

Publications
Javed S, Selliah T, Lee YJ, Huang WH (2020) Dosage-Sensitive Genes in Autism Spectrum Disorders: From Neurobiology to Therapy. Neuroscience and Biobehavioral Reviews; S0149-7634(20)30547-9.doi: 10.1016/j.neubiorev.2020.08.009

Graves JD, Lee YJ, Liu K, Li G, Lin FT, Lin WC (2020) E2F1 sumoylation as a protective cellular mechanism in oxidative stress response. Proc Natl Acad Sci; 117(26):14958-14969. doi: 10.1073/pnas.1921554117. Epub 2020 Jun 15

Liu K, Graves JD, Lee YJ, Lin FT, Lin WC (2020) Cell cycle-dependent switch of TopBP1 functions by Cdk2 and Akt. Mol Cell Biol; 40:E00599-19. PMID: 31964753, PMCID: PMC7108819

Lee YJ, Ho SR, Graves JD, Xiao Y, Huang S, Lin WC (2019) CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer. Breast Cancer Res; 21:134. PMID: 31801577, PMCID: PMC6894136
 
Liu K, Lin FT, Graves JD, Lee YJ, Lin WC (2017) Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin. Proc Natl Acad Sci; 114:E3766-E3775. PMCID:PMC5441733, PMID:28439015
 
Ho SR, Lee YJ, Lin WC (2015) Regulation of RNF144A E3 ubiquitin ligase activity by self-association through its transmembrane domain. J Biol Chem; 290:23026-38. PMCID: PMC4645615, PMID: 26216882
 
Ho SR, Mahanic CS, Lee YJ, Lin WC (2014) RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage. Proc Natl Acad Sci; 111:E2646-2655. PMCID:PMC4084471, PMID: 24979766