Minza Haque​, M.Sc.

• M.Sc. in Biochemistry, McGill University, Canada
• B.Sc. in Biochemistry, Mount Holyoke College, USA
• 2021 Alan Edwards PhD Studentship
• ​2024, 2025 RI-MUHC Studentship
• 2025 RI-MUHC EDI Prize for Academic Excellence
  
• Minza is interested in studying the molecular and neural mechanisms underlying ASD/epilepsy genes​

Publications:
​Chang YT, Lee YJ, Haque M, Chang HC, Javed S, Lin YC, Abramovitz J, Chin G, Khamis A, Raja R, Murai KK, Huang WH
Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys
J Comp Neurol., 2024 Jan;532(1):e25589. doi: 10.1002/cne.25589.​

Javed S, Chang YT, Cho Y, Lee YJ, Chang HC, Haque M, Lin YC, Huang WH
Smith-Magenis syndrome protein Rai1 regulates body weight homeostasis through hypothalamic Bdnf-producing neurons and neurotrophin downstream signalling
Elife, 2023;12:RP90333. doi.org/10.7554/eLife.90333.3
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Chang HC, Lee YJ, Javed S, Haque M, Chang YT, Lin YC, Oram C, Huang WH 
rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice
J Biol Chem, 2023 Jan, doi: 10.1016/j.jbc.2022.102728

Chang YT, Kowalczyk M, Fogerson PM, Lee JY, Haque M, Adams EL, Wang DC, DeNardo LA, Tessier-Lavigne M, Huguenard JR, Luo L, Huang WH
Loss of Rai1 enhances hippocampal excitability and epileptogenesis in mouse models of Smith-Magenis syndrome
Proc Natl Acad Sci USA, 2022 Oct, doi.org/10.1073/pnas.2210122119
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