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Debbie Ya-Ting Chang, Ph.D.
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Publications
Chang HC, Lee YJ, Javed S, Haque M, Chang YT, Lin YC, Oram C, Huang WH
rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice
J Biol Chem, 2023 Jan, doi: 10.1016/j.jbc.2022.102728
Chang YT, Kowalczyk M, Fogerson PM, Lee JY, Haque M, Adams EL, Wang DC, DeNardo LA, Tessier-Lavigne M, Huguenard JR, Luo L, Huang WH
Loss of Rai1 enhances hippocampal excitability and epileptogenesis in mouse models of Smith-Magenis syndrome
Proc Natl Acad Sci USA, 2022 Oct, doi.org/10.1073/pnas.2210122119
Chang, Y.T., Ling J, Gu JG. (2021) Effects of GABA B receptor activation on excitability of IB4-positive maxillary trigeminal ganglion neurons: Possible involvement of TREK2 activation. Mol. Pain doi: 10.1177/17448069211042963.
Kanda H, Ling J, Chang, Y.T., Erol F, Viatchenko-Karpinski V, Yamada A, Noguchi K, Gu JG. (2021) Kv4.3 channel dysfunction contributes to trigeminal neuropathic pain manifested with orofacial cold hypersensitivity in rats. J Neurosci. doi: 10.1523/JNEUROSCI.2036-20.2021.
Chang C.S., Liao, C.C., Liou A.T., Chang Y.S., Chang, Y.T., Tzeng, B.H., Chen, C.C., Shih, C. (2019) Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model. Sci.Reports.9:11108
Chang, Y.T., Chen W.H., Shih, H. C., Min, M.Y., Shyu, B.C., and Chen, C.C. (2019) Anterior nucleus of paraventricular thalamus mediates chronic mechanical hyperalgesia. Pain.160(5):1208-1223. (Editor’s Choice)
Chen W.H., Chang, Y.T., Chen, Y.C., Cheng, S.J., and Chen, C.C. (2018) Spinal protein kinase C/extracellular signal-regulated kinase signal pathway mediates hyperalgesia priming. Pain. 159(5):907-918
Cheng, Y.F.*, Chang, Y.T.*, Chen, W.H., Shih, H. C. Chen, Y. H., Shyu, B.C., and Chen, C.C. (2017) Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus. Nature Communications. 8:826. (*The authors contributed equally to this work)
Chang, Y.M., Ling, L., Chang, Y.T, Chang, Y. W., Li, W. H., Shih, A. C. & Chen., C. C. (2017) Three TF Co-expression Modules Regulate Pressure-Overload Cardiac Hypertrophy in Male Mice. Scientific Reports. 7: 7560
Chang, Y.W., Chang, Y.T., Wang, Q., Lin, J., Chen,Y.J. & Chen,C.C.(2013) Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy. Mol Cell Proteomics,12(11):3094-107
Hsu, S.C., Chang, Y.T. & Chen, C.C. (2013) Early Growth Response 1 is an Early Signal Inducing Cav3.2 T-type Calcium Channels during Cardiac Hypertrophy. Cardiovasc Res, 100(2):222-30
Cheng, S.J., Chen, C.C., Yang, H.W., Chang,Y.T., Bai, S.W., Chen, C.C., Yen, C.T. & Min, M.Y. (2011) Role of extracellular signal-regulated kinase in synaptic transmission and plasticity of a nociceptive input on capsular central amygdaloid neurons in normal and acid-induced muscle pain mice. J Neurosci 2011, 31(6):2258 –2270
Chen, W.G., Liu,I.Y., Chang, Y.T., Chen, Y.C., Chen,C.C., Yen, C.T., Shin, H.-S., & Chen, C.C. (2010) Cav3.2 T-type Ca2+ channel dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain. J Neurosci 2010, 30(31):10360-10368 (evaluated by Faculty of 1000 Medicine)
Chiang, C.S. Huang, C. H., Chieng, H.L, Chang, Y.T., Chang, D., Chen, J.J., Chen, Y.C., Chen, Y.H., Shin, H.-S., Campbell, K.P., & Chen, C.C. (2009) Cav3.2 T-type Ca2+ channel is required for pressure overload-induced cardiac hypertrophy in mice. Circ Res 104(4). 522-530. (evaluated by Faculty of 1000 Biology and Faculty of 1000 Medicine)
Chang HC, Lee YJ, Javed S, Haque M, Chang YT, Lin YC, Oram C, Huang WH
rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice
J Biol Chem, 2023 Jan, doi: 10.1016/j.jbc.2022.102728
Chang YT, Kowalczyk M, Fogerson PM, Lee JY, Haque M, Adams EL, Wang DC, DeNardo LA, Tessier-Lavigne M, Huguenard JR, Luo L, Huang WH
Loss of Rai1 enhances hippocampal excitability and epileptogenesis in mouse models of Smith-Magenis syndrome
Proc Natl Acad Sci USA, 2022 Oct, doi.org/10.1073/pnas.2210122119
Chang, Y.T., Ling J, Gu JG. (2021) Effects of GABA B receptor activation on excitability of IB4-positive maxillary trigeminal ganglion neurons: Possible involvement of TREK2 activation. Mol. Pain doi: 10.1177/17448069211042963.
Kanda H, Ling J, Chang, Y.T., Erol F, Viatchenko-Karpinski V, Yamada A, Noguchi K, Gu JG. (2021) Kv4.3 channel dysfunction contributes to trigeminal neuropathic pain manifested with orofacial cold hypersensitivity in rats. J Neurosci. doi: 10.1523/JNEUROSCI.2036-20.2021.
Chang C.S., Liao, C.C., Liou A.T., Chang Y.S., Chang, Y.T., Tzeng, B.H., Chen, C.C., Shih, C. (2019) Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model. Sci.Reports.9:11108
Chang, Y.T., Chen W.H., Shih, H. C., Min, M.Y., Shyu, B.C., and Chen, C.C. (2019) Anterior nucleus of paraventricular thalamus mediates chronic mechanical hyperalgesia. Pain.160(5):1208-1223. (Editor’s Choice)
Chen W.H., Chang, Y.T., Chen, Y.C., Cheng, S.J., and Chen, C.C. (2018) Spinal protein kinase C/extracellular signal-regulated kinase signal pathway mediates hyperalgesia priming. Pain. 159(5):907-918
Cheng, Y.F.*, Chang, Y.T.*, Chen, W.H., Shih, H. C. Chen, Y. H., Shyu, B.C., and Chen, C.C. (2017) Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus. Nature Communications. 8:826. (*The authors contributed equally to this work)
Chang, Y.M., Ling, L., Chang, Y.T, Chang, Y. W., Li, W. H., Shih, A. C. & Chen., C. C. (2017) Three TF Co-expression Modules Regulate Pressure-Overload Cardiac Hypertrophy in Male Mice. Scientific Reports. 7: 7560
Chang, Y.W., Chang, Y.T., Wang, Q., Lin, J., Chen,Y.J. & Chen,C.C.(2013) Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy. Mol Cell Proteomics,12(11):3094-107
Hsu, S.C., Chang, Y.T. & Chen, C.C. (2013) Early Growth Response 1 is an Early Signal Inducing Cav3.2 T-type Calcium Channels during Cardiac Hypertrophy. Cardiovasc Res, 100(2):222-30
Cheng, S.J., Chen, C.C., Yang, H.W., Chang,Y.T., Bai, S.W., Chen, C.C., Yen, C.T. & Min, M.Y. (2011) Role of extracellular signal-regulated kinase in synaptic transmission and plasticity of a nociceptive input on capsular central amygdaloid neurons in normal and acid-induced muscle pain mice. J Neurosci 2011, 31(6):2258 –2270
Chen, W.G., Liu,I.Y., Chang, Y.T., Chen, Y.C., Chen,C.C., Yen, C.T., Shin, H.-S., & Chen, C.C. (2010) Cav3.2 T-type Ca2+ channel dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain. J Neurosci 2010, 30(31):10360-10368 (evaluated by Faculty of 1000 Medicine)
Chiang, C.S. Huang, C. H., Chieng, H.L, Chang, Y.T., Chang, D., Chen, J.J., Chen, Y.C., Chen, Y.H., Shin, H.-S., Campbell, K.P., & Chen, C.C. (2009) Cav3.2 T-type Ca2+ channel is required for pressure overload-induced cardiac hypertrophy in mice. Circ Res 104(4). 522-530. (evaluated by Faculty of 1000 Biology and Faculty of 1000 Medicine)